Faculty Research Profile
Jung-Seok Kim
학력
· 2016~2021: Ph.D., Department of Immunology, Weizmann Institute of Science, Israel
· 2013~2016: M.Sc., Department of Immunology, Weizmann Institute of Science, Israel
· 2006~2013: B.S., Life Science, Handong Global University, Korea
주요 경력
· 2025~present: Assistant Professor, Department of Biological Sciences, Ulsan National Institute of Science and Technology, Korea
· 2022~2025: Research Associate, Department of Regenerative Biology and Immunology, Weizmann Institute of Science., Israel
· 2021~2022: Post-Doctoral Fellow, Department of Immunology, Weizmann Institute of Science, Israel
수상/학회/외부활동
· 2023: Korea Association of Immunologists International meeting 2023, Travel Awards
· 2021: Korea Society for Molecular and Cell Biology International Conference, Young Investigator’s Awards
신경면역 연구실
Lab. of Neuroimmunology
신경면역 연구실은 독특한 중추신경계의 면역 시스템 특징을 이해하고, 이를 바탕으로 알츠하이머병이나 파킨슨병과 같은 퇴행성 뇌질환과 중추신경에서 발생하는 자가면역질환의 발생 기전을 면역학적인 접근 방법으로 분석하고 이해하는 연구를 수행하고 있습니다. 특별히 중추신경계에 존재하는 면역 세포 중 선천성 면역의 대표인 대식세포에 속한 미세아교세포 (microglia)와 경계 연관 대식세포 (border-associated macrophage: BAM)를 중심으로 연구를 수행하고 있습니다. 뿐만 아니라 중추신경 내에서 선천성 면역과 적응 면역의 가교 역할을 담당하는 항원제시 세포를 중심으로, 중추신경계의 경계 부에 존재하는 T 세포들과 상호작용에 관심을 가지고 있습니다.
The Neuroimmunology laboratory is dedicated to understanding the unique characteristics of the immune system within the central nervous system (CNS). We aim to uncover the immunological mechanisms underlying the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, as well as CNS-related autoimmune disorder. Our research primarily focuses on CNS-resident innate immune cells, particularly microglia and border-associated macrophages (BAMs), which are main macrophage populations in the CNS. In addition, we are interested in antigen-presenting cells in the CNS that serve as a bridge between innate and adaptive immunity.
The Neuroimmunology laboratory is dedicated to understanding the unique characteristics of the immune system within the central nervous system (CNS). We aim to uncover the immunological mechanisms underlying the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, as well as CNS-related autoimmune disorder. Our research primarily focuses on CNS-resident innate immune cells, particularly microglia and border-associated macrophages (BAMs), which are main macrophage populations in the CNS. In addition, we are interested in antigen-presenting cells in the CNS that serve as a bridge between innate and adaptive immunity.
연구분야
신경면역, 선천성 면역, 항원제시세포, 퇴행성 뇌질환, 자가면역질환
Neuroimmunology, Innate Immunity, Antigen-Presenting cells, Neurodegenerative diseases, Autoimmune Diseases
연구 희망분야
중추신경에 존재하는 면역세포의 역할을 알아내고, 이를 바탕으로 퇴행성 뇌질환과 자가면역질환의 치료를 위한 새로운 전략 수립
Establishing therapeutic strategy for neurodegenerative and autoimmune diseases in the CNS
연구주제
· 중추신경 혈관 발생과정에서 면역세포의 역할
· 병리적 상황에서 면역세포의 중추신경 침투 과정
· 퇴행성 뇌질환에서 면역세포의 역할
· Function of immune cells for the development of blood vessels in the CNS
· Processes of immune cells infiltration to the CNS in the pathologic conditions
· Pathologic roles of immune cells in the neurodegenerative diseases
· Function of immune cells for the development of blood vessels in the CNS
· Processes of immune cells infiltration to the CNS in the pathologic conditions
· Pathologic roles of immune cells in the neurodegenerative diseases
국가연구개발사업 기술 분류체계
국가과학기술표준분류
LA. 생명과학 > LA04. 면역학·생리학 > LA0402. 선천성 면역
논문
· Cell Rep. Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice. Kim, J.-S. et al. (2025.01)
· Glia. Not just Glia—Dissecting brain macrophages in the mouse. Frumer, G. R., Shin, S., Jung, S. & Kim, J-S. (2024.07)
· Immunity. A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages. Kim, J.-S. et al. (2021.01)
특허
N/A