Faculty Research Profile
Sung Kuk Lee
학력
• 2001: Ph.D. School of Environmental Science and Engineering, Pohang University of Science and Technology(POSTECH), Korea
• 1997: M.S. Department of Life Science, POSTECH, Korea
• 1994: B.S. Department of Microbiology, Kyungbook National University, Korea
주요 경력
• 2008 - Present: Assistant, Associate, Professor, UNIST
• 2007 - 2008: Co-Director, Fuel Synthesis Division, Joint BioEnergy Institute (JBEI)
• 2004 - 2007: Associate Specialist II, Department of Chemical Engineering, UC Berkeley and Synthetic Biology Department, SynBERC/LBNL
• 2001~2004 : Postdoctoral Fellow, Department of Chemical Engineering, UC Berkeley
수상/학회/외부활동
• 2021 & 2022: The Best Article Award from BBE
• 2012: URP 장려상 수상
• 2012: Best Paper Award from BBE
• 2011: Silver medal in 2011 iGEM regional competition at Hong Kong
• Editorial Board, Biotechnology and Bioprocess Engineering (BBE) & Journal of Microbiology and Biotechnology (JMB)
• Committee Member, The Korean Society for Biotechnology and Bioengineering (KSBB, 한국생물공학회)
• Committee Member, The Korean Society for Microbiology and Biotechnology (KMB, 한국미생물생명공학회)
합성생물학 및 대사공학 연구실
Synthetic Biology & Metabolic Engineering Lab
지구온난화의 주범인 석유화학산업을 대체할 친환경 미래 기술로 ‘바이오 리파이너리’가 주목받고있다. 이에 본 연구실에서는 여러 유전공학 및 합성생물학 기술들을 개발하고 활용하여 바이오매스로부터 다양한 바이오 화학물질들을 생산할 수 있는 인공미생물을 제작하는 대사 공학 연구를 진행하고 있다.
My research interests generally lie in the metabolic pathway engineering, the use of recombinant DNA technology to modify existing, or to introduce entirely new, metabolic pathways and regulatory systems within cells in order to improve their capacity to overproduce desired molecules (Biofuels, Bioplastics, Chemicals, Drugs).
My research interests generally lie in the metabolic pathway engineering, the use of recombinant DNA technology to modify existing, or to introduce entirely new, metabolic pathways and regulatory systems within cells in order to improve their capacity to overproduce desired molecules (Biofuels, Bioplastics, Chemicals, Drugs).
연구분야
대사공학, 합성생물학, 바이오리파이너리 / Metabolic engineering, Synthetic biology, Biorefinery
Metabolic engineering, Synthetic biology, Biorefinery
연구 희망분야
바이오연료, 바이오신약, 바이오케미컬, 바이오플라스틱 / Biofuels, Bioplastics, Chemicals, Drugs
Biofuels, Bioplastics, Chemicals, Drugs
연구주제
• [대사공학] 최적의 바이오화학물질 생산 대사경로 설계 및 최적화
Design and optimization of metabolic pathways for biochemical production
• [합성생물학] 고성능/고효율의 인공미생물 제작 기술 개발
Development of synthetic biology tools to build artificial biological systems
• [바이오리파이너리] 바이오매스 기반 고가의 바이오화학물질 생산
Microbial cell factories for oil palm biomass-based biorefinery
• Design and optimization of metabolic pathways for biochemical production
• Development of synthetic biology tools to build artificial biological systems
• Microbial cell factories for oil palm biomass-based biorefinery
국가연구개발사업 기술 분류체계
국가과학기술표준분류
EC. 화공 > EC04. 생물화학공정기술 > EC0402. 대사공학기술
논문
• BIORESOURCE TECHNOLOGY / Production of polyhydroxyalkanoates by the thermophile Cupriavidus cauae PHS1 / An, Jung Vin; Ha, Bo Ram; Lee, Sung Kuk/ 2023-03
• BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS / Characterization of an Entner-Doudoroff pathway-activated Escherichia coli / Kim, Ye Eun; Cho, Kyung Hyun; Bang, Ina; Kim, Chang Hee; Ryu, Young Shin; Kim, Yuchan; Choi, Eun Mi; Nong, Linh Khanh; Kim, Donghyuk; Lee, Sung Kuk / 2022-11
• JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY / Improving free fatty acids production in Escherichia coli by combinatorial metabolic engineering / Park, Woo Sang; Shin, Kwang Soo; Jung, Hyun Wook; Lee, Yong Joo; Chandran, Sathesh-Prabu; Lee, Sung Kuk / 2022-10
• BIORESOURCE TECHNOLOGY / Metabolic engineering of Escherichia coli for 2,3-butanediol production from cellulosic biomass by using glucose-inducible gene expression system/ Chandran, Sathesh-Prabu; Kim, Donghyuk; Lee, Sung Kuk/ 2020-08
특허
• Method for preparing mutant Escherichia coli capable of simultaneously utilizing glucose and xylose / Sung Kuk Lee, Goohee Kim, Seong Hun Jeong, Suk Min Kim, and Bae Young Choi / [등록번호]US Patent No. 9,284,582 (03/15/2016 ~ 07/02/2034)
• Mutant microorganism with enhanced sugar utilization and methods for preparing the same / Sung Kuk Lee, and Parisutham Vinuselvi / [등록번호]US Patent No. 8,871,480 (10/28/2014 - 07/25/2033)