Faculty Research Profile
Semin Lee
학력
· 2011: Department of Biochemistry, University of Cambridge, PhD
· 2005: Department of Bio and Brain, Engineering, KAIST, MSc
· 2003: School of Biological Sciences, Seoul National University, BA
주요 경력
· 2020~ Present: Department of Biomedical Engineering, UNIST, Associate Professor
· 2016~2020: School of Life Sciences, UNIST, Assistant Professor
· 2011~2016: Department of Biomedical Informatics, Harvard Medical School, Research Fellow
계산생물학 실험실
Computational Biology Lab
We analyze a large number of cancer genomes using multiple omics approaches to characterize various kinds of germline/somatic alterations in many different human cancer types. In order to understand somatic mosaicism, heterogeneity, and evolution in cancer, we also use single-cell genomics approaches.
We analyze a large number of cancer genomes using multiple omics approaches to characterize various kinds of germline/somatic alterations in many different human cancer types. In order to understand somatic mosaicism, heterogeneity, and evolution in cancer, we also use single-cell genomics approaches.
연구분야
Cancer genomics, single-cell omics, Structural bioinformatics, Machine learning, Precision medicine
Cancer genomics, single-cell omics, Structural bioinformatics, Machine learning, Precision medicine
연구 희망분야
Rare disease genomics, Immunogenomics
Rare disease genomics, Immunogenomics
연구주제
암유전체학, 단일세포오믹스, 구조생명정보학, 기계학습, 정밀의학
Cancer genomics, single-cell omics, structural bioinformatics, machine learning, precision medicine
Cancer genomics, single-cell omics, structural bioinformatics, machine learning, precision medicine
국가연구개발사업 기술 분류체계
국가과학기술표준분류
LA. 생명과학 > LA07. 융합바이오 > LA0706. 생물정보학
논문
· Sci. Adv., Korean Genome Project: 1,094 Korean personal genomes with clinical information, Jeon S, Bhak Y, Choi Y, et al. (2020.05)
· Acta Neuropathologica, Genomic analysis reveals secondary glioblastoma after radiotherapy in a subset of recurrent medulloblastomas, Ji Hoon Phi, Ae Kyung Park, Semin Lee, et al., (2018.06)
· Science, Mosaic Mutations Trace Developmental and Transcriptional Histories of Single Human Neurons, Lodato MA, Woodworth MB, Lee S, Evrony GD, Mehta BK, Karger A, Lee S, Chittenden TW, Cai X, Luquette LJ, Lee E, Park PJ, Walsh CA., (2015.10)