Faculty Research Profile
Jinmyoung Joo
학력
· 2012: Ph. D. Chemical Engineering, POSTECH
· 2007: B. S. Chemical Engineering, POSTECH
주요 경력
· 2022~present: Associate Professor, UNIST
· 2019~2022: Assistant Professor, UNIST
· 2016~2018: Assistant Professor, University of Ulsan College of Medicine
· 2013~2016: Postdoctoral Research Associate, University of California, San Diego
· 2012~2013: Postdoctoral Research Fellow, Institute of Environmental and Energy Technology, POSTECH
수상/학회/외부활동
· 2021: Lee Sang Hoon Academic Award, KBCS
· 2021: Miwon Commercial Young Investigator, KSIEC
· 2019: POSCO TJ Park Science Fellow
· 2019: Emerging Investigator, Royal Society of Chemistry, UK
· 2018~Present: Education and Accreditation Committee, Korean BioChip Society
· 2019~Present: Academic Program Committee, Korean Society of Medical and Biological Engineering
· 2023~Present: Academic Program Committee, Korean Society for Biomaterials
생체 재료 및 중개 의학 연구실
Laboratory for Biomaterials and Translational Medicine
생체 재료 및 중개 의학 연구실은 다양한 기능성 나노 소재를 활용한 진단 및 치료 플랫폼 개발을 위해, 생체 시스템에 대한 이해와 신소재 설계를 중점적으로 연구하고 있다. 궁극적으로는 의학적으로 임상에서 활용 가능한 중개의학 시스템을 개발하고자 하며, 세포 표면 수용체 반응 및 신호 전달 프로세스부터 조직 미세환경에 이르는 광범위한 생체 시스템을 이해함으로서 질병의 조기 진단 및 치료를 이끌어 낼 수 있는 바이오메디컬 툴(tool)을 제시하는 것을 목표로 한다. 단백질과 DNA, 펩타이드 등 생물학적 기본 구성 요소와 비슷한 크기와 기능을 가지는 나노소재를 활용함으로서, 각종 질병의 진단과 치료에 연관된 생물학적 과정을 이해할 수 있고, 이를 바탕으로 신경 질환, 암, 감염병 등의 질환을 효과적으로 치료할 수 있는 의학적 개념을 제시할 수 있다. 특히, 나노소재의 표면 및 생체 시스템과의 계면에서 발생하는 물리-화학적 상호 작용의 열역학적 이해와 동역학적 원리를 근본적으로 이해함으로써 나노-생체소재의 중개의학적 활용을 이끌 수 있다.
The lab focuses on utilization of functional nanomaterials in diagnostic and therapeutic platforms and finds governing principles for biomedical materials design. Ultimate goals are starting from these findings and set a cutting-edge foundation of engineering sophisticated “multiscale biomedical material systems” for translational applications. In order to achieve the goals, we emphasize fundamental understandings of how nano-structured materials interact with biological systems. We also investigate the thermodynamic and kinetic basis of physicochemical interactions between synthetic biomedical materials and complex biological systems, with a specific focus on the surface chemistry and interface engineering.
The lab focuses on utilization of functional nanomaterials in diagnostic and therapeutic platforms and finds governing principles for biomedical materials design. Ultimate goals are starting from these findings and set a cutting-edge foundation of engineering sophisticated “multiscale biomedical material systems” for translational applications. In order to achieve the goals, we emphasize fundamental understandings of how nano-structured materials interact with biological systems. We also investigate the thermodynamic and kinetic basis of physicochemical interactions between synthetic biomedical materials and complex biological systems, with a specific focus on the surface chemistry and interface engineering.
연구분야
나노-바이오 소재, 약물 전달 시스템, 바이오이미징, 중개의학 / Nano-bio materials, Drug delivery systems, Bioimaging, Biosensor, Translational medicine, Tissue regeneration
Nano-bio materials, Drug delivery systems, Bioimaging, Biosensor, Translational medicine, Tissue regeneration
연구 희망분야
생체소재, 생분해성 나노신소재, 질병 조기 진단 및 표적 치료 / Biomaterials, Biodegradable materials, Medical diagnosis, Precision medicine
Biomaterials, Biodegradable materials, Medical diagnosis, Precision medicine
연구주제
나노-바이오공학 시스템, 의생명소재, 나노-바이오 계면 공학, 바이오센서, 약물 전달 시스템, 재생 의학, 생체 영상, 계면 화학, 분자 공학, 유전자 치료
Systems Nano-Bioengineering, Biomedical Materials, Nano-Bio interface, Biosensor, Drug Delivery Systems, Regenerative Medicine, Bioimaging, Surface Chemistry, Molecular Engineering, Gene Therapy
Systems Nano-Bioengineering, Biomedical Materials, Nano-Bio interface, Biosensor, Drug Delivery Systems, Regenerative Medicine, Bioimaging, Surface Chemistry, Molecular Engineering, Gene Therapy
국가연구개발사업 기술 분류체계
국가과학기술표준분류
LC. 보건의료 > LC03. 의약품·의약품개발 > LC0309. 약물전달시스템
논문
· ACS Nano, Aptamer nanoconstructs crossing human blood-brain barrier discovered via microphysiological system-based SELEX technology (2023)
· Journal of Nanobiotechnology, Secured delivery of basic fibroblast growth factor using human serum albumin-based protein nanoparticles for enhanced wound healing and regeneration (2023)
· Nanoscale, Tailored polyethylene glycol grafting on porous nanoparticles for enhanced targeting and intracellular siRNA delivery (2022)
· Nature Biomedical Engineering, Antibiotic-loaded nanoparticles targeted to the site of infection enhance antibacterial efficacy (2018)
· Advanced Materials, Tracking the fate of porous silicon nanoparticles delivering a peptide payload by intrinsic photoluminescence lifetime (2018)